I’m not exactly sure what you’re after here.
I’m assuming you have a custom field that asks a User a question in their profile?
Then, based on their answer, you’d like different content displayed?
If so, you’d do it like this (depending on what you’re after):
If they’ve filled in the field:
{if custom_field_1}This will show {custom_field_1} contents{/if}
If you’re after showing content based on say, a Yes/No field:
{if custom_field_1 == "yes"}This will show {custom_field_1} contents.{/if}
If you’re after different content being displayed per type of answer submitted:
{if custom_field_1 == "pies"}You love to eat Pies!{/if}
{if custom_field_1 == "cheesies"}You love to eat Cheesies!{/if}
{if custom_field_1 == "donkey"}You love to eat Donkeys!{/if}